White Willow Bark Extract Salicin

Premium Grade Botanical Ingredient for Pharmaceuticals, Nutraceuticals & Cosmeceuticals

White Willow Bark Extract Salicin is a high-purity, botanical-derived active ingredient manufactured through advanced extraction and spray-drying processes. Sourced from the natural bark, branches, and stems of Salix species, this ingredient is standardized to contain ≥98% Salicin, presented as a highly refined white crystalline powder.

Known historically as nature’s precursor to aspirin, Salicin ($\text{C}{13}\text{H}{18}\text{O}_7$, CAS No: 138-52-3) delivers reliable analgesic, antipyretic, and anti-inflammatory support. Extract Makers supplies bulk, high-grade White Willow Bark Extract tailored for pharmaceutical formulators, dietary supplement manufacturers, and cosmetic innovators requiring rigorous quality standards, complete traceabilty, and lot-to-lot consistency.

Technical Specifications & Product Profile

Analytical Quality & Purity Assurance

At Extract Makers, every batch of White Willow Bark Extract undergoes comprehensive laboratory testing to satisfy stringent international standard requirements, including the European Pharmacopoeia (Eur.Ph.) and United States Pharmacopeia (USP).

Chemical & Physical Analysis

• Assay (Salicin by HPLC): ≥ 98.0% (Batch Result: 98.16%)
• Loss on Drying: ≤ 5.0% (Batch Result: 2.21%)
• Total Ash: ≤ 5.0% (Batch Result: 1.05%)
• Particle Size: 100% pass 80 mesh (Conforms)
• Residual Solvents: Fully compliant with Eur.Ph.7.0 <5.4> and <2.4.24>
• Pesticide Residues: Fully compliant with USP36 <561> requirements

Heavy Metal Limits (ICP-MS Tested)

• Total Heavy Metals: ≤ 10.0 ppm (Eur.Ph.7.0 <2.2.58>)
• Lead (Pb): ≤ 2.0 ppm
• Arsenic (As): ≤ 1.0 ppm
• Cadmium (Cd): ≤ 1.0 ppm
• Mercury (Hg): ≤ 0.5 ppm

Microbiological Parameters

• Total Plate Count: ≤ 1,000 cfu/g (USP <2021>)
• Total Yeast & Mold: ≤ 100 cfu/g (USP <2021>)
• Escherichia coli: Negative / 10g (USP <2021>)
• Salmonella species: Negative / 10g (USP <2021>)

Primary Applications & Industry Uses

Salicin is a versatile glucoside compound recognized for its gentle biological pathways. Upon ingestion, salicin is metabolized into salicylic acid, providing sustained pain relief and anti-inflammatory actions without causing the sharp gastric distress frequently linked to synthetic acetylsalicylic acid (aspirin).

1. Dietary Supplements & Nutraceuticals

• Joint Health & Mobility Formulations: Serves as a key botanical ingredient in formulations targeting joint discomfort, flexibility, and anti-inflammatory support.
• Natural Pain Management: Used as a herbal alternative to standard OTC analgesics, particularly in products designed for chronic back pain, tension headaches, and muscular soreness.
• Active Life & Recovery Blend: Frequently blended into post-workout recovery formulas to alleviate exercise-induced stiffness.

2. Cosmetics & Skincare (Cosmeceuticals)

• Gentle Exfoliation & Clarifying Formulations: Naturally rich in salicylic acid precursors, it helps clear pores, smooth skin texture, and reduce excess sebum production.
• Soothing & Anti-Redness Serums: Ideal for sensitive, acne-prone, or irritated skin conditions due to its natural anti-inflammatory activity.

3. Pharmaceutical Preparations

• Utilized as a high-purity natural precursor and active botanical raw material in antipyretic (fever-reducing) and pain-relieving medicinal formulations.

Regulatory Compliance & Quality Statements

To assist brand owners and procurement managers with compliance and smooth market entry, Extract Makers provides full regulatory backing for our White Willow Bark Extract Salicin 98%:

• Non-GMO Statement: Produced entirely from non-GMO plant materials without recombinant DNA technology.
• By-Products & Impurities Clearance: Free from parabens, phthalates, volatile organic compounds (VOCs), and residual harmful solvents.
• Gluten-Free Certification: Manufactured without gluten-containing ingredients, safe for celiac-friendly product lines.
• BSE/TSE Free: Completely free of Transmissible Spongiform Encephalopathy and Bovine Spongiform Encephalopathy risks.
• Cruelty-Free: Not tested on animals at any stage of production.
• Dietary Compliance: Certified Kosher and Vegan compliant.

Food Allergen Matrix

Why Partner with Extract Makers?

As a dedicated B2B manufacturer and global ingredient supplier, Extract Makers specializes in providing consistent, high-purity plant extracts for wholesale distributors, formulation scientists, and international brands.

• Standardized Potency: HPLC-verified 98% purity ensures accurate dosing in finished health and wellness products.
• Green Extraction Methods: Processed using clean ethanol and hydro-extraction techniques to preserve bioactivity while eliminating hazardous chemical residues.
• Full Documentation: Every shipment includes a complete Certificate of Analysis (CoA), Safety Data Sheet (SDS), and technical specifications.
• Scalable Bulk Supply: Secure supply chain options packaged to maintain stability, extend shelf life, and protect against humidity.

Contact Our B2B Sales & Technical Support Team

Ready to integrate premium White Willow Bark Extract Salicin 98% into your product line? Request samples, obtain custom quotes, or consult with our formulation experts directly:

• Commercial Inquiries: [email protected]
• Technical Support: Available for custom mesh sizes, bulk packaging configurations, and regulatory documentation assistance.

Emily